SYNDER V0.2-4B-2540M Filtration Pvdf Microfiltration 0.2UM Membrane 2.5 38

( Brand: Synder ), ( Manufacturer Part Number: V0.2-4B-2540M ), ( Spacer Size: 65 Mil ), ( Micron Rating: 0.2 Micron ), ( Filter Material: Pvdf ), ( Dimensions: 2.5 In X 38 In ), ( Membrane Area: 17 Sq Ft ), ( Maximum Flow Rating: 12 Gpm ), ( Max Operating Temperature: 140 F ), ( Unit Type: Unit ), ( Outerwrap: Control Bypass Without Tail ), ( Connection Type: Male P.w.t. ), ( Filter Type: Filter Element ), ( Sn: 127071453 ), ( Country Of Origin: United States )

Review SYNDER Filtration Pvdf Microfiltration Membrane 2.5 Inch 38

The **Synder V0.2-4B-2540M 0.2-micron Polyvinylidene Fluoride (PVDF) Microfiltration Membrane** is a high-performance, sterile-grade filtration solution designed for demanding laboratory, bioprocessing, and pharmaceutical applications where precision, durability, and reliability are paramount. Engineered with **PVDF**, a chemically resistant and biocompatible polymer, this membrane excels in filtering particles, bacteria, and fine contaminants while maintaining exceptional mechanical stability under repeated sterilization cycles. The **0.2-micron nominal pore size** ensures consistent retention of most bacteria and submicron particles, making it ideal for sterile filtration of aqueous solutions, cell culture media, buffers, and sensitive biological samples without compromising the integrity of target molecules. With a **2.5-inch diameter**, this membrane offers a compact yet efficient filtration surface, perfect for small-scale applications such as sample preparation, vaccine production, or analytical testing where space and throughput optimization are critical.

The **4B-2540M** designation indicates a **sterile, pre-sanitized membrane** that has undergone rigorous quality control, including gamma irradiation or ethylene oxide sterilization, ensuring immediate use without additional sterilization steps. Its **hydrophilic surface** promotes rapid wetting and consistent flow rates, reducing clogging and extending membrane lifespan particularly valuable in applications involving viscous or particulate-heavy solutions. The membrane s **high flux performance** and low protein-binding characteristics further enhance its suitability for biopharmaceutical processes, where recovery of delicate biomolecules like proteins, antibodies, or vaccines is essential. Additionally, PVDF s resistance to harsh chemicals, including acids, bases, and organic solvents, makes this membrane versatile for a wide range of filtration tasks, from sterile filtration of pharmaceutical formulations to the clarification of complex biological matrices.

Constructed with **durable, non-fibrous PVDF**, this membrane resists swelling, shrinking, or deformation under pressure, ensuring consistent filtration performance across a broad operating range. Its **rigid yet flexible structure** allows for easy handling and compatibility with standard filtration devices, including syringe filters, vacuum manifolds, and inline systems. The **2.5-inch format** strikes a balance between practicality and efficiency, accommodating a variety of lab-scale applications while minimizing waste. Whether used for **pre-filtering** to protect downstream processes, **sterile filtration** of cell culture media, or **clarification** of sensitive biological samples, this membrane delivers reliable, repeatable results with minimal maintenance. Its compatibility with both **hot and cold sterilization methods** including autoclaving further extends its utility in environments where contamination control is non-negotiable. For researchers, bioprocess engineers, and quality assurance teams, the **Synder V0.2-4B-2540M** represents a robust, high-integrity filtration solution that bridges the gap between performance and practicality in critical applications.

### **Pros and Cons of buying a Synder V0.2-4B-2540M Filtration Membrane (0.2 m PVDF Microfiltration)**

1. **High Filtration Efficiency** The 0.2 m pore size effectively removes bacteria, colloids, and fine particles, making it suitable for applications requiring sterile or high-purity filtration (e.g., bioprocessing, cell culture, or lab work).

2. **Durable Material (PVDF)** Polyvinylidene fluoride (PVDF) is chemically resistant to most solvents, acids, and bases, ensuring long-term stability in harsh environments. It also has good thermal resistance, allowing use in a wide temperature range.

3. **Compatibility with Autoclaving** Unlike some membranes, PVDF can withstand autoclaving (steam sterilization), making it ideal for sterile filtration in biotech and pharmaceutical applications.

4. **Low Protein Binding** PVDF has minimal non-specific protein adsorption, reducing contamination risks in biological filtrations (e.g., vaccine production, antibody purification).

5. **Reusable Potential** Depending on the application, some PVDF membranes can be cleaned and reused, reducing long-term costs compared to disposable alternatives.

6. **High Flow Rates** The membrane s design (likely optimized for throughput) allows for efficient filtration, reducing processing time in large-scale applications.

7. **Versatile Applications** Suitable for sterile filtration, clarification, and pre-filtration in industries like biopharmaceuticals, food and beverage, and environmental monitoring.

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1. **Cost** PVDF membranes are generally more expensive than alternatives like cellulose or nylon, which may limit budget-conscious applications.

2. **Limited Pore Size Flexibility** The fixed 0.2 m pore size may not be optimal for applications requiring finer or coarser filtration (e.g., virus removal would need a smaller pore size).

3. **Potential Fouling** Like all membranes, PVDF can foul over time with proteins, lipids, or particulates, requiring backflushing or cleaning, which adds maintenance effort.

4. **Mechanical Fragility** While durable chemically, PVDF membranes can be brittle if mishandled (e.g., sharp edges, improper storage), risking damage during use or storage.

5. **Compatibility Issues with Certain Solvents** Though resistant to many chemicals, PVDF may degrade in strong oxidizers (e.g., concentrated sulfuric acid) or high concentrations of certain solvents.

6. **Disposal Considerations** If not reusable, disposing of PVDF membranes may require special handling due to their synthetic nature, adding environmental or regulatory compliance costs.

7. **Supplier Dependence** Availability and pricing may vary by region, and reliance on a specific brand (Synder) could limit flexibility if alternatives are needed.

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The **Synder V0.2-4B-2540M PVDF membrane** is a high-performance option for applications demanding **sterility, chemical resistance, and durability**, particularly in **biopharmaceutical, lab, or industrial filtration**. Its advantages in **autoclave compatibility, low protein binding, and broad chemical resistance** make it ideal for critical processes where contamination control is paramount. However, its **higher cost, potential fouling, and limited pore size flexibility** may not justify its use in low-cost or low-complexity applications.

- You require **sterile or high-purity filtration** (e.g., cell culture, vaccine production, lab work).

- Your process involves **harsh chemicals or autoclaving**, where PVDF s resistance is essential.

- You prioritize **long-term durability and reusability** over disposable alternatives.

- Your budget is tight (e.g., cellulose or nylon membranes may suffice for less demanding applications).

- You need **finer filtration** (e.g., 0.1 m for virus removal) or **coarser filtration** (e.g., 0.45 m for general clarification).

- Your process involves **solvents that degrade PVDF** (e.g., strong oxidizers).

For most **biotech, pharmaceutical, or sterile filtration needs**, this membrane is a **strong, reliable choice**. However, always verify compatibility with your specific solvents, flow rates, and regulatory requirements before purchasing.

Details:

The filter element features a control bypass without tail design and male P.W.T. Defective items may only be exchanged for the same title. The Synder Filtration V0.2-4B-2540M PVDF 0.2UM Microfiltration Membrane is a high-quality filter element designed for use in hydraulic systems. Made of durable PVDF material with a 0.2 micron rating, this 2.5 x 38 membrane offers large 17 sq ft area and maximum flow rating 12 gpm.

Synder Filtration V0.2-4B-2540M PVDF 0.2UM Microfiltration Membrane 2.5 x 38. With a maximum operating temperature of 140 F, this unit is ideal for industrial applications and proudly manufactured in the USA by Synder Filtration. Products Most of our photos are the actual item you purchasing. Unless stated otherwise in the listing.

Connection type for easy installation and maintenance.

part #: v024b2540m price

• $633.05

specifications hydraulivalv:

• brand: Synder
• mpn: V0.2-4b-2540m
• spacer size: 65 Mil
• micron rating: 0.2 Micron
• filter material: Pvdf
• dimensions: 2.5 In X 38 In
• membrane area: 17 Sq Ft
• maximum flow rating: 12 Gpm
• max operating temperature: 140 F
• unit type: Unit
• outerwrap: Control Bypass Without Tail
• connection type: Male P.w.t.
• filter type: Filter Element
• sn: 127071453
• country of origin: United States

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• # reviews: 13718
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• quantity: 1
• started: April 30, 2026
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general hydraulivalv:

• Hydraulics, Pneumatics, Pumps Plumbing > Hydraulic Filters Cartridges > Filter Cartridges Elements
• condition: New

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